Quantitative Sudomotor Axon Reflex Test (QSART)

Quantitative Sudomotor Axon Reflex Test (QSART) is a test to evaluate the integrity of the postganglionic sudomotor system along the axon reflex to define the distribution of sweat loss. This is accomplished by the release of acetycholine into the skin which activates receptors on the eccrine sweat gland. The sweat response is recorded from four sites (forearm and 3 lower extremity sites) and assessed for deficits.

The QSART is a test that measures the autonomic nerves that control sweating. The test is useful in assessing autonomic nervous system disorders, peripheral neuropathies and some types of pain disorders. The test requires a mild electrical stimulation on the skin called iontophoresis, which allows acetylcholine, a naturally occurring chemical, to stimulate sweat glands. The QSART measures the volume of sweat produced by this stimulation.

QSART is used to diagnose:

- Painful, small fiber neuropathy when nerve conduction test results are normal
- Disturbances of the autonomic nervous system, which controls the sweat glands, heart, digestive system, other organs, and blood pressure
- Complex pain disorders
- Diabetic neuropathies
- Enzyme disorders
- RSD (Reflex Sympathetic Dystrophy, Complex Regional Pain Syndrome)
- Dysautonomia
- Pharmaceutical agents
- Cosmetics/Consumer goods testing
- Dermatological studies
- Multiple System Atrophy (Shy-Drager syndrome)

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Sympathetic Skin Response (SSR)

Sympathetic Skin Response (SSR) measures change of the electrical potential of the skin. The recorded skin potential comes from the activated eccrine sweat gland. The amplitude and configuration are adjusted by sweat gland epithelium and the overlying epidermis.

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Sudomotor sympathetic response

VitalScan SudoCheck+ provides information that determines the cardiometabolic risk in patients. The test, equivalent to a galvanic skin response stress test, measures the sweat glands' capacity to release chloride ions in response to an electrochemical activation.
The advantages: VitalScan SudoCheck+ does not require any patient preparation, such as blood drawing or fasting; it is non-invasive and delivers immediate results, with findings that are ready to use after a short and uncomplicated test of merely 2 minutes.
VitalScan SudoCheck+ has been developed for use by general practitioners, pharmacists, cardiologists and neurologists to assist in the effective screening of cardiometabolic risk in patients.Read More

Bioelectric Impedance Analysis (BIA)

As a physician, you know that the Body Mass Index (BMI) by itself is not sufficient to analyze a patient's health status and body composition thoroughly.
Fat, muscle, water and other important indicators of underlying medical conditions are not considered in the BMI.
Reason enough for Medeia to develop exactly that - a new device that measures patients' body compositions - the "BCA" (Body Composition Analyzer). As a component of the VitalScan SudoCheck+, it produces all these measurements and values at medical science highest standard levels.

As a result, now a tool exists that, in less than 20 seconds, can determine fat mass, extracellular and intracellular water, and skeletal muscle mass, all fundamental assessment components to aid an accurate patient evaluation. Simple, user friendly, and with medical precision, this device can conveniently be integrated into your examination routine.

In order to make VitalScan SudoCheck+ the optimal medical Body Composition Analyzer for working conditions in hospitals and medical practices, we looked beyond the many technical requirements and at the advantages and benefits that are valuable and of importance to medical staff and patients. We understood it had to be fast and easy to use and the measurement results had to be reproducible under normal clinical working conditions. That's' how we designed and build VitalScan SudoCheck+.

The VitalScan SudoCheck+ provides physicians and other users with a myriad of diagnostic options. Analytical modules provide accurate ratios for, for example extracellular to intracellular water, or fat mass to weight, and present doctors with indications of medical disorders that would otherwise need additional examinations to be diagnosed. The graphic presentation of the results is another benefit. It provides a summary and overview and helps visualize the data.

Bioelectric Impedance Analysis (BIA) is for research use only.

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Electro Interstitial Scan

It is recommended to test the functions of the device before measurement, to ensure that the connection to the patient is satisfactory and hardware and software are operating properly. With the onset of measurement, a weak DC current (200 uA) is used and an imposed voltage of 1V between the six tactile electrodes that performs a sequence of successive measurements on eleven pathways of the body. Starting from anode to cathode and then from cathode to anode, the software changes the polarity for each pathway and measures the conductance of each pathway. Six electrodes are placed symmetrically on the hands, feet and forehead of the patient and a direct current of 1V is applied. For a recording of 11 segments in measurement sequence, each electrode is first in cathode and then in anode (bipolar mode), transmitting the intensity in numeric format to a program that stores the information.
A weak DC current, with the help of 6 tactile electrodes, is sending alternatively between 2 electrodes with a sequence, and a record of the electrical conductance of 11 pathways in the subject's body is displayed by the VitalScan SudoCheck+ system.
The VitalScan SudoCheck+ system is a galvanic Skin response device that provides skin conductance measurements on the PC screen in accordance with the 21 CFR 882.1540.

The device uses two techniques: The Bio Impedance Analysis (BIA) and the Bio Impedance Spectrometry (BIS).
The purpose of BIA is the estimation of body composition and water balance but it is also used in cardiology and imaging.
The BIS is another technique for the estimation the body composition and water balance, but it can also be used to estimate neurotransmitters.

Electro Interstitial Scan is for research use only.

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